2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

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Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-168570
    Insecticidal agent 16
    		Inhibitor
    Insecticidal agent 16 (compound A21) is a potent insecticidal agent. Insecticidal agent 16 shows insecticidal activities against Plutella xylostella and Spodoptera frugiperda with LC50 values of 1.2 and 13.2 µg/mL, respectively.
    Insecticidal agent 16
  • HY-138502
    Melarsomine
    		Inhibitor
    Melarsomine is a trivalent arsenical compound used as an adulticide. Melarsomine can be used for the reserach of canine heartworm disease and other helminth infections.
    Melarsomine
  • HY-14603R
    Clioquinol (Standard)
    Clioquinol (Standard) is the analytical standard of Clioquinol. This product is intended for research and analytical applications. Clioquinol (Iodochlorhydroxyquin) is a topical antifungal agent with anticancer activity. Clioquinol acts as an oral antimicrobial agent for the research of diarrhea and skin infections. Antibiotic.
    Clioquinol (Standard)
  • HY-79504
    Ferrocene
    		Inhibitor 98.0%
    Ferrocene is an important structural core in bioorganometallic chemistry because of its inherent stability, excellent redox properties, and low toxicity. Ferrocene has antimalarial and anticancer properties.
    Ferrocene
  • HY-B1751S
    Quinidine-d3
    		Inhibitor
    Quinidine-d3 is the deuterium labeled Quinidine. Quinidine is an antiarrhythmic agent for the treatment of abnormal heart rhythms and also malaria.
    Quinidine-d<sub>3</sub>
  • HY-117179
    Endosulfan sulfate
    		Inhibitor
    Endosulfan sulfate is the major metabolite of the insecticide Endosulfan, used for various crops. Endosulfan sulfate is more toxic and persistent than Endosulfan.
    Endosulfan sulfate
  • HY-174343
    ELQ-121
    		Inhibitor
    ELQ-121 is a potent inhibitor of the ubiquinol-oxidation (QO)-site of parasites. ELQ-121 has IC50 of 0.05 nM against chloroquine sensitive and multidrug resistant P. falciparum in vitro. ELQ-121 inhibits T. gondii and N. caninum with IC50 below 1 nM in vitro. ELQ-121 suppresses B. besnoiti tachyzoite proliferation with an IC50 of 0.49 nM and induces mitochondrial disruption. ELQ-121 can form polyethylene glycol carbonate ester prodrug which demonstrates in vivo efficacy against P. yoelii in mice. ELQ-121 is suitable for antimalarial research.
    ELQ-121
  • HY-B0803S
    Lumefantrine-d18
    		Inhibitor
    Lumefantrine-d18 is the deuterium labeled Lumefantrine, which is an antimalarial agent.
    Lumefantrine-d<sub>18</sub>
  • HY-W014394R
    Vanillyl butyl ether (Standard)
    Protoporphyrin IX (Standard) is the analytical standard of Protoporphyrin IX. This product is intended for research and analytical applications. Protoporphyrin IX is a final intermediate in the heme biosynthetic pathway, which acts as a radiation sensitizer enhancing ROS generation even in a hypoxic state and inducing DNA damage. Protoporphyrin IX also acts as a photo sensitizer undergoing photobleaching that occurs through direct degradation by light irradiation. Protoporphyrin IX is formed and accumulated following 5-aminolevulinic acid (5-ALA) (HY-W000450) administration in the tumor cells of rats. Protoporphyrin IX causes selective improvement of basal cell carcinoma when activated red fluorescence of a peak wavelength at 405 nm. Protoporphyrin IX is promising for research of sonodynamic and photodynamic agents for a wide range of cancers, such as bladder cancer and nodular basal cell carcinoma.
    Vanillyl butyl ether (Standard)
  • HY-B1004R
    Dinitolmide (Standard)
    		Inhibitor
    Dinitolmide (Zoalene) (Standard) is the analytical standard of Dinitolmide (HY-B1004). This product is intended for research and analytical applications. Dinitolmide is an orally active anticoccidial agent used as a fodder additive. Dinitolmide has a wide anticoccidial spectrum with no effect on host immunity. Dinitolmide mainly acts on the first generation merozoite stage of coccidia and also has an inhibitory effect on the sporulation process of oocysts. Dinitolmide has anti-Toxoplasma gondii effect in vitro with an EC50 of 3.625 μg/mL. Dinitolmide can be used to inhibits infections caused by Eimeria tenella.
    Dinitolmide (Standard)
  • HY-P5696
    Xenopsin precursor fragment
    		Inhibitor
    Xenopsin precursor fragment is an antimicrobial peptide, and has antibacterial/antifungal (10-500 μg/mL) and anti-protozoal (MIC: 2-20 μg/mL) activity.
    Xenopsin precursor fragment
  • HY-N3247
    Monomethyl kolavate
    		Inhibitor
    Monomethyl kolavate is a Trypanosoma brucei GAPDH enzyme (TbGAPDH) inhibitor with theIC50 value of 2 µM.
    Monomethyl kolavate
  • HY-169445
    (±)-Meclonazepam
    		Control
    (±)-Meclonazepam ((±)-Ro 11-3128) is the racemate of Meclonazepam (HY-101725). Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect. Meclonazepam exhibits antischistosomal activity against S. mansoni.
    (±)-Meclonazepam
  • HY-144098
    HDAC8-IN-2
    		Inhibitor
    HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor, with IC50 values of 0.27 and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. HDAC8-IN-2 shows significant killing of the schistosome larvae. HDAC8-IN-2 markedly impairs egg laying of adult worm pairs.
    HDAC8-IN-2
  • HY-139672
    BRD5018
    		Inhibitor
    BRD5018 is an antimalarial agent. BRD5018 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    BRD5018
  • HY-N3378
    Lipiferolide
    		Inhibitor
    Lipiferolide is an antiplasmodial agent (IC50: 1.8 μg/mL) that can be isolated from Liriodendron tulipifera. Lipiferolide also inhibits FPTase, and has antitumor activity.
    Lipiferolide
  • HY-114614
    Clenpirin
    		Inhibitor
    Clenpirin is a insecticide against cattle ticks Boophilus microplus. Clenpirin exhibits slightly toxicity to rats with LD50 of 3050 mg/kg.
    Clenpirin
  • HY-W1004917
    8,9-Z-Abamectin B1a
    		Inhibitor
    8,9-Z-Abamectin B1a is the 8,9-Z-isomer of Abamectin B1a (HY-15308). Avermectin B1a is an antiparasitic agent that paralyzes nematodes.
    8,9-Z-Abamectin B1a
  • HY-161666
    mCMY416
    		Inhibitor
    mCMY416 is an orally active and blood brain barrier (BBB) permeability apicomplexan phenylalanine tRNA synthetase inhibitor, and shows antiparasitic activity .
    mCMY416
  • HY-159097
    T.cruzi-IN-4
    		Inhibitor
    T.cruzi-IN-4 (Compound 21) is an anti-parasitic agent. T.cruzi-IN-4 inhibits the trypomastigote and amastigote form of Trypanosoma cruzi with IC50 of 0.033 μM (120 h), T.cruzi-IN-4 inhibits the promastigote and amastigote form of Leishmania infantum with IC50 of 28.74 and 61.82 μM. T.cruzi-IN-4 inhibits Leishmania amazonensis promastigote form with IC50 of 18.38 μM.
    T.cruzi-IN-4
Parasite Isoform Comparison

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